Carrying the theme of “Harnessing the Immune System”, the 29st Annual Congress of the Asia Pacific Blood and Marrow Transplantation Group (APBMT) were held in Singapore from 10th to 13th October 2024. The annual congress is primarily a scientific meeting, enabling all professionals with an interest in blood and marrow transplantation and other blood cell therapies within the region to present their research findings and drive the whole field change.

 

As the core technology in the field of hematology，hematopoietic stem cell transplantation has strong and well-tested clinical curative effects for a long time, saving the lives of a growing number of people. Meanwhile，as a new frontier technology, CAR-T therapy is carrying more and more patients’ expectations with its powerful efficacy, and reviving the hope of patients with blood diseases that were once difficult to cure.

 

Targeting unmet patient needs, GoBroad Medical Team proudly presented 10 research achievements in the APBMT Annual Congress this year, exploring the new frontiers of CAR-T and hematopoietic stem cell transplantation with innovative strategies. For a long time, the team has focused on developing more abundant and accessible treatment options for patients with blood diseases, especially those with relapse and refractory diseases.

 

 

Oral

 

Title 1: Efficacy and toxicity for CD7 chimeric antigen receptor T-cell therapy in patients with relapsed/refractory T-cell lymphoma

 

Authors: Fan Yang¹, Hui Shi¹, Rui Liu¹, Ruiting Li¹, Biping Deng², Xiaoyan Ke¹, Kai Hu ¹

Institution: 1 Beijing GoBroad Hospital  2 Beijing GoBroad Boren Hospital

Key words: Refractory/relapsed T-cell lymphoma; CD7 CAR-T cell Therapy; CRS; Cytopenias; Infection

 

 

Title 2: The outcome of CAR-T therapy for central nervous system lymphoma following failed autologous hematopoietic stem cell transplantation

 

Authors: Rui Liu，Zhonghua Fu，Fan Yang，Xiaoyan Ke，Kai Hu

Institution: Beijing GoBroad Hospital

 

 

Title 3: TCRαβ-depleted Haplo-HSCT following CAR-T Therapy improves GVHD-free/Relapse-free Survival in Pediatric R/R-ALL

 

Authors: Huaying Liu, Dejun Chen, Jing Wang, Simeng Lv , Yuelin He, Chunfu Li Institution: Nanfang-Chunfu Children’s Institute of Hematology

 

 

Poster

 

Title 1 : Application of mNGS in the clilnical diagnosis and treatment of infectious diseases after allogeneic hematopoietic stem cell transplantation in patients with recurrent refractory malignant hematologic diseases

 

Authors: Lei Wang, Zhihui Li, Keyan Yang, Jingjing Wang, Xiaopei Wen, Qian Fei, Xianxuan Wang, Jing Li, Zongyang Ming, Tong Wu

Institution: Beijing GoBroad Boren Hospital

 

 

 

 

 

Title 2: Letermovir is used to prevent CMV infection after secondary HSCT in patients with hematological malignancies, single-center real-world experience

 

Authors: Xianxuan Wang, Zhihui Li, Keyan Yang, Jingjing Wang, Xiaopei Wen, Qian Fei, Lei Wang, Jing Li, Tong Wu

Institution：Beijing GoBroad Boren Hospital

 

 

Title 3 : Long-term Outcome of the Second Allogeneic Hematopoietic Stem Cell Transplantation in Hematological Malignancies with Reduced Toxicity Conditioning and Donor Change

 

Authors: Yongqiang Zhao, Rui Wang, Feifei Li, Dongfang Yang, Fang Fang, Yanzhi Song, Zhihui Li, Fan Yang and Tong Wu

Institution：Beijing GoBroad Boren Hospital

 

 

Title 4: Secondary Salvage Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) in Relapsed and Refractory AML

 

Authors: Yanzhi Song, Zhanxiang Liu, Erhui Yuan, Qishu Qin, Kong Gao, Qiuhao Fu, Qi Wang, Tong Wu

Institution: Beijing GoBroad Boren Hospital

 

 

Title 5: Low-dose CD22 Monoclonal Antibody Bridging to Allogeneic Hematopoietic Stem Cell Transplantation for Acute B Lymphoblastic Leukemia in Non-Remission or Minimal Residual Disease Positive after CD19 or CD22 CART-Cell Therapy

 

Authors: Erhui Yuan, Yanzhi Song, Zhanxiang Liu, Qishu Qin, Lihong An,Yuehui Lin, Shuangyou Liu, Tong Wu

Institution: Beijing GoBroad Boren Hospital

 

 

Title 6: Safety and Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation with Teniposide Containing Conditioning in Patients of Hematologic Malignancies with Extramedullary Diseases

 

Authors: Fang Fang, Rui Wang, Feifei Li, Dongfang Yang, Yongqiang Zhao and Tong Wu

Institution: Beijing GoBroad Boren Hospital

Keywords: allo-HSCT, Hematologic Malignancy, Tiniposide, Conditioning

 

 

Title 7: Nursing Experience of a Severe AML Patient with Secondary HSCT Skin

Infection Caused by Fusarium

 

Authors: Shuyue Xu, Xiaoxia Wang, Kun Xu, Dandan Song, Zixuan Liang, Lidong Cheng, Lei Wang, Zhihui Li, Tong Wu

Institution: Beijing GoBroad Boren Hospital