The patient was a 34-year-old Pakistani man and father of two. He was life-threatened due to acute b-lymphocytic leukemia in 2023. He had poor response to 5 periods of chemotherapy locally and rapidly deteriorated, so he was recommended CAR-T cell therapy. In January 2023, the patient came to GHG medical center and immediately started debulking chemotherapy because the bone marrow examination showed a very high proportion of tumor cells. CD19-CAR-T cell refusion was performed after the proportion of tumor cells was reduced to 0%.

During the treatment, the patient experienced acute cytokine release syndrome(CRS), but uneventfully passed the critical period under immediate treatment. After 14 days of CAR-T therapy, the proportion of tumor cells was successfully reduced to 0%, the patient improved significantly and was discharged uneventfully in February 2024.